Sickle Cell is not an illness, however, all people should be tested to see if they will pass the sickle gene to their children. Genes are passed from parents to their children.
It's very important to get tested. You should know your hemoglobin type. You only have to take the test once in your life.
Prosper Foundation for Sickle Cell
P. O. Box 940184
Plano, Texas 75094
Facts About Sickle Cell Disease
SCD is a group of inherited red blood cell disorders. Healthy red blood cells are round, and they move through small blood vessels to carry oxygen to all parts of the body. In someone who has SCD, the red blood cells become hard and sticky and look like a C-shaped farm tool called a “sickle”. The sickle cells die early, which causes a constant shortage of red blood cells. Also, when they travel through small blood vessels, they get stuck and clog the blood flow. This can cause pain and other serious problems such infection, acute chest syndrome and stroke.
Types of SCDFollowing are the most common types of SCD:
HbSSPeople who have this form of SCD inherit two sickle cell genes (“S”), one from each parent. This is commonly called sickle cell anemia and is usually the most severe form of the disease.
HbSCPeople who have this form of SCD inherit a sickle cell gene (“S”) from one parent and from the other parent a gene for an abnormal hemoglobin called “C”. Hemoglobin is a protein that allows red blood cells to carry oxygen to all parts of the body. This is usually a milder form of SCD.
HbS beta thalassemiaPeople who have this form of SCD inherit one sickle cell gene (“S”) from one parent and one gene for beta thalassemia, another type of anemia, from the other parent. There are two types of beta thalassemia: “0” and “+”. Those with HbS beta 0-thalassemia usually have a severe form of SCD. People with HbS beta +-thalassemia tend to have a milder form of SCD.
There also are a few rare types of SCD:
HbSD, HbSE, and HbSOPeople who have these forms of SCD inherit one sickle cell gene (“S”) and one gene from an abnormal type of hemoglobin (“D”, “E”, or “O”). Hemoglobin is a protein that allows red blood cells to carry oxygen to all parts of the body. The severity of these rarer types of SCD varies.
Sickle Cell Trait (SCT)HbASPeople who have SCT inherit one sickle cell gene (“S”) from one parent and one normal gene (“A”) from the other parent. This is called sickle cell trait (SCT). People with SCT usually do not have any of the signs of the disease and live a normal life, but they can pass the trait on to their children. Additionally, there are a few, uncommon health problems that may potentially be related to sickle cell trait.
Learn more about sickle cell trait »
Cause of SCD: SCD is a genetic condition that is present at birth. It is inherited when a child receives two sickle cell genes—one from each parent.
Diagnosis: SCD is diagnosed with a simple blood test. It most often is found at birth during routine newborn screening tests at the hospital. In addition, SCD can be diagnosed before birth.
Because children with SCD are at an increased risk of infection and other health problems, early diagnosis and treatment are important.
You can call your local sickle cell organization to find out how to get tested.
Complications and Treatments: People with SCD start to have signs of the disease during the first year of life, usually around 5 months of age. Symptoms and complications of SCD are different for each person and can range from mild to severe.
There is no single best treatment for all people with SCD. Treatment options are different for each person depending on the symptoms.
Learn about complications and treatments »
Cure: The only cure for SCD is bone marrow or stem cell transplant.
Bone marrow is a soft, fatty tissue inside the center of the bones where blood cells are made. A bone marrow or stem cell transplant is a procedure that takes healthy cells that form blood from one person—the donor—and puts them into someone whose bone marrow is not working properly.
Bone marrow or stem cell transplants are very risky, and can have serious side effects, including death. For the transplant to work, the bone marrow must be a close match. Usually, the best donor is a brother or sister. Bone marrow or stem cell transplants are used only in cases of severe SCD for children who have minimal organ damage from the disease.
To be committed to total wellness through nutrition and supplementation for preventive health and management f Sickle Cell Disease.
What is Sickle Cell Disease?
Sickle Cell Disease is an inherited disease that affects our hemoglobin. Inherited means it is passed from mothers and fathers to their children. Hemoglobin is a special protein substance inside the red blood cells that is responsible for carrying oxygen from the lungs and takes it to every part of the body. Every person has two copies of the hemoglobin gene. A change in the hemoglobin from the normal hemoglobin type may cause the symptoms of Sickle Cell Disease. Hemoglobin also gives blood its rich red color.